Standard approach to fight with viruses is to use antigens which
search for some specific place on the surface, but the problem is that
the capsid is varying rapidly.
What usually doesn't change is that the virus still targets to the
same molecules on cell's surface - maybe we should try to use it.
For example create empty liposome: water + phospholipid with specific
molecules - for example CD4 and some chemokine receptors for HIV.
Now if the virus would catch the bait, it will enter inside and loose
its capsid - even if the liposome will be destroyed - it shouldn't
longer be a threat or at least much smaller than it would be swimming
in capsid. Eventually we could add inside for example reverse
transcriptaze
inhibitor or some RNA cutting enzyme.
Imagine such stealth liposom with CD4 - it should swim through veins
for a few hours catching viruses, than be consumed with it's content
by the immune system - perfect scenario.
And remember that every HIV virus has some version of gp120 - should
catch the bait...
