Hyperviscosity of the blood leads to .. inflammatory symptoms /
markers .. soooo .. the inflammation found in these mice .. is no
surprise / "unsuspected link" to those who .. **KNOW** .. ? ..
hyperviscosity leads TO inflammatory .. markers / symptoms.

<<snip>>
chronic inflammation is associated with hyperlipidemia
<<snip>>

Link found between immune system and high plasma lipid levels

April 13, 2007 - Researchers at the University of Chicago have found
an unsuspected link between the immune system and high plasma lipid
levels (cholesterol and triglycerides in the blood) in mice. The
finding could lead to new ways to reduce the risk of heart disease by
lowering elevated lipid levels.

In the April 13, 2007, issue of Science, the research team-led by
James C. Lo, an MD, PhD student, in the laboratory of Yang-Xin Fu, MD,
PhD, professor of pathology at the University of Chicago-suggest that
an engineered protein could keep mice, and possibly humans, from
developing high cholesterol and triglyceride levels, a key risk factor
for coronary heart disease.

"Besides showing a link between the immune system and elevated lipids,
this study also opens a new avenue for the study of the close and
complex link between elevated blood lipid levels and chronic
inflammation as manifest in coronary heart disease, ," said Fu, senior
author on the paper. "It reveals a quite unexpected role of hepatic T
cells in lipid metabolism."

"Those with inflammatory problems such as lupus, rheumatoid arthritis
and inflammatory bowel syndrome have a higher incidence of
cardiovascular disease, often associated with elevated lipid levels,"
added co-author Godfrey Getz, MD, PhD, professor of pathology,
biochemistry and molecular biology at the University of Chicago. "This
study may explain why. The next step would be to determine whether we
can use this technique to manipulate the immune response and have a
favorable impact on lipid metabolism."

Using an assortment of engineered and non-engineered mice, the
researchers looked specifically at the role of T cells (white blood
cells that play a key role in immunity). They determined that altering
the expression level of LIGHT (a specific type of molecule that binds
to a receptor site of another cell) and also lymphotoxin (LT) on T
cells significantly impacted the cholesterol and triglyceride levels.

When T cells expressing LIGHT were introduced into the mice, lipid
levels rose, both when the mice were fed a regular diet, and also when
fed a high-fat, high-cholesterol diet. However, if researchers blocked
the LIGHT signaling, using an engineered protein (LTbR-Ig), lipid
levels were lowered again.

Two organs believed to regulate lipid levels are the liver and the
intestine. Researchers looked at the mouse livers - particularly at
the enzyme, hepatic lipase. This enzyme is made in the liver and
secreted into the blood where it plays a key role in lipid metabolism.
The livers of mice with T cells expressing LIGHT made and secreted
much less hepatic lipase - and consequently, had higher plasma lipid
levels.

The authors write: "Our data may help to explain the long time dogma
that chronic inflammation is associated with hyperlipidemia, the
mechanisms of which have not been well defined. Whether this is an
intended and advantageous product of inflammation or untoward
consequences of combating pathogens or autoimmunity remains to be
determined."

University of Chicago Medical Center

Who loves ya.
Tom


Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

"Hyperviscosity of the blood leads to .. inflammatory symptoms /
markers .. soooo .. the inflammation found in these mice .. is no
surprise / "unsuspected link" to those who .. **KNOW** .. ? ..
hyperviscosity leads TO inflammatory .. markers / symptoms."

The article said nothing about "viscosity".

Jesus ate a mediterranean diet.

How OFTEN .. do you HAVE to exhibit .. **stupidity** .. ?

hyperlipidemia

I suppose in your .. world .. the world of the medical professional ..
you are UNABLE to .. fkg .. think .. ?

You don't .. **think** .. hyperlipidemia .. manifests ..
hyperviscosity .. ?

Do you KNOW what .. **viscosity** .. is .. ?

Obviously .. not ..

Heh .. heh ..

Now .. FO .. I'm REALLY getting tired of your .. stupidity ..

You KNOW .. that .. ?

It irks me .. man ..

I think I told you that .. before ..

Stupidity .. irks me .. man ..


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

"Joan Carter" <spamfree@sentex.ca> wrote in message
news:muuae31ngf65pv6e2rrjna5p7725h6r764@4ax.com...
On Mon, 10 Sep 2007 09:58:02 -0700, ironjustice
<teamtanner@hotmail.com> wrote:

They are not the same, Tommy, get with the program.

*** exactly! and this is exactly why newbies and lurkers need to be warned
about believing what rustyrump pretends to know!


hy·per·lip·id·emia -"lip-&-'dE-mE-&

"noun, the presence of excess fat or lipids in the blood"

© 2006 Merriam-Webster, Inc.
Merriam-Webster's Medical Desk Dictionary, 3rd Edition


hyperlipidemia-hi'per-lip'i-de'me-a

"Elevated levels of lipids in the blood plasma. There are several types of
hyperlipemia. One is associated with a deficiency of ?-aminoadipic
semialdehyde synthase."

© 2006 Lippincott Williams & Wilkins
Stedman's Medical Dictionary, 28th Edition



kate

<teamtan...@hotmail.com> wrote:
You don't .. **think** .. hyperlipidemia .. manifests ..
hyperviscosity .. ?
They are not the same, Tommy, get with the program. <<

Read my lips .. all of you ..

You are .. stupid ..

You should NOT .. comment .. ON .. **my** threads ..

It irks me .. man ..

Especially .. THOSE .. who SPECIFICALLY .. refer to their ..
**medical** .. professionalism .. because .. ? .. you evidence ..
stupidity .. AT ALL TIMES ..

Viscosity is the thickness of the fluid .. the fluid is made thicker
when you add a viscous substance to it .. lipids are .. viscous ..
soooooo .. hyperlipidemia WILL manifest .. hyperviscosity ..

It takes NO .. rocket scientist to determine .. THAT ..

A fkg .. two year old can tell .. using LOGIC and REASON ..

Look .. basic .. science ..

<<snip>>
abnormal CBF reserve associated with hyperlipidemia is due to increase
blood viscosity
<<snip>>

Basic Science Reports


Decrease in Coronary Blood Flow Reserve During Hyperlipidemia Is
Secondary to an Increase in Blood Viscosity
Se-Joong Rim, MD; Howard Leong-Poi, MD; Jonathan R. Lindner, MD; Kevin
Wei, MD; Nicholas G. Fisher, MD; Sanjiv Kaul, MD

Correspondence to Sanjiv Kaul, MD, Cardiovascular Division, Box
800158, Medical Center, University of Virginia, Charlottesville, VA
22908. E-mail sk@virginia.edu

Background- During maximal hyperemia, capillaries provide the greatest
resistance to flow. A major determinant of capillary resistance is
viscosity. We, therefore, hypothesized that abnormal coronary blood
flow (CBF) reserve observed during hyperlipidemia is secondary to
increased blood viscosity and not abnormal coronary vasomotion.

Methods and Results- Maximal hyperemia was induced in 9 dogs using
adenosine. Serum triglyceride levels were increased by incremental
doses of Intralipid. A good correlation was noted between serum
triglyceride levels and blood viscosity (r=0.82). Neither total
coronary blood volume nor myocardial blood volume changed with
increasing serum triglyceride levels, indicating lack of vasomotion.
Myocardial vascular resistance (MVR) increased with increasing
triglyceride levels (r=0.84), while hyperemic myocardial blood flow
(MBF) decreased (r=-0.64). The decrease in hyperemic MBF was
associated with a decrease in blood velocity (r=-0.56). These findings
were confirmed with direct intravital microscopic observations in the
mice cremaster muscle.

Conclusions- Increasing lipid levels in a fully dilated normal
coronary bed causes no change in large or small vessel dimensions.
Instead, the increase in blood viscosity causes capillary resistance
to rise, which attenuates hyperemic CBF. Therefore, the abnormal CBF
reserve associated with hyperlipidemia is due to increase blood
viscosity and not abnormal vascular function.


Key Words: risk factors · lipids · microcirculation


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

On Mon, 10 Sep 2007 13:04:58 -0700, numbnutz tommy <teamtanner@hotmail.com>
wrote:

The only moron in this group is you. Everyone else has at least a
double-digit IQ.



You've been told before, you don't own anything posted in newsgroups.

They are PUBLIC domain and anyone is free to comment on any post.

If you don't like that, start your own moderated group in which you can
control posts, something like alt.support.numbnutz.moderated.


.... An ostrich's eye is bigger than its brain (just like numbnutz tommy).

Soooo .. NOW .. you **hint** at .. you were / are FULLY aware .. ? ..
hyperlipidemia IS hyperviscosity .. ?

Is that what you are .. hinting .. at .. ?

Either way .. cow .. you have no REASON to BE .. on .. this thread ..

Do .. ya ..

Either you don't KNOW .. hyperlipidemia IS hyperviscosity .. OR .. you
did .. and you .. lied ..

Now lying and medical professionalism has been shown in NUMEROUS ..
case studies .. to go hand in hand ..

Sooo .. seeing you hold out to BE .. a medically trained
professional .. I will assume you .. **lied** ..

Heh .. heh ..

What a fkg .. loser ..

NOW .. stay off my threads .. because .. ? .. you have EVIDENCED
your .. sociopathic .. tendencies .. TOO MANY FKG TIMES ..

Ya .. dig .. ?


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

On Sep 10, 3:54 pm, "california_chief"
<Fire_Chief@Jamacha_Junction_FD.ca.us> wrote: You've been told before,
you don't own anything posted in newsgroups. <<

AND .. evidenced .. stupidity .. WHICH .. I .. gladly POINT .. out ..
is NOT .. **acceptable** BY .. **those** who express ..
**specifically** .. medical .. "expertise".

Which .. evidence based SHOWS .. clearly .. they DON'T .. have ..

You somehow figure .. doctors / nurses and the like .. who are full of
sht .. SHOULD be allowed to .. lie .. and exhibit .. stupidity ..
whereas .. ME .. ? .. have NO tolerance FOR .. stupidity ..

I then advise .. them .. NOT to show their stupidity .. any
**more** .. by .. ? .. Fkg O ..

And then there is .. you ..

How come I am not surprised you RUSH to .. defend .. stupidity ..

Because without .. stupidity .. you would BE .. nothing .. stupidity
is what DEFINES .. **you** ..

Look into .. it ..

On Sep 10, 1:04 pm, ironjustice <teamtan...@hotmail.com>
wrote:Viscosity is the thickness of the fluid .. the fluid is made
thicker
when you add a viscous substance to it .. lipids are .. viscous ..
soooooo .. hyperlipidemia WILL manifest .. hyperviscosity .. <<

This is the html version of the file http://www.indianpediatrics.net/apr2007/306.pdf.

http://www.google.com/search?q=cache...t= clnk&cd=14
hyperlipidemia hyperviscosity



--------------------------------------------------------------------------------


CASE REPORTS INDIAN PEDIATRICS 306VOLUME44__APRIL17, 2007
Encephalopathy in Type I Hyperlipidemia


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

"ironjustice" <teamtanner@hotmail.com> wrote in message
news:1189469296.613841.4350@k79g2000hse.googlegrou ps.com...
Soooo .. NOW .. you **hint** at .. you were / are FULLY aware .. ? ..
hyperlipidemia IS hyperviscosity .. ?

Is that what you are .. hinting .. at .. ?

Either way .. cow .. you have no REASON to BE .. on .. this thread ..

Do .. ya ..

Either you don't KNOW .. hyperlipidemia IS hyperviscosity .. OR .. you
did .. and you .. lied ..

Now lying and medical professionalism has been shown in NUMEROUS ..
case studies .. to go hand in hand ..

Sooo .. seeing you hold out to BE .. a medically trained
professional .. I will assume you .. **lied** ..

Heh .. heh ..

What a fkg .. loser ..

NOW .. stay off my threads .. because .. ? .. you have EVIDENCED
your .. sociopathic .. tendencies .. TOO MANY FKG TIMES ..

Ya .. dig .. ?


Who loves ya.
Tom

ROTFLOL! joan's actually absolutely correct, rusty rump! you really ARE so
predictable! but, you're totally blinded by rust and can't see it clearly,
eh?

hint, hint--"if it looks like, sounds like and acts like a . . ."
mindlessly obsessive, raving lunatic, then it is a . . . quack, quack,
quack, quack, quack.

you make it soooo easy to press your buttons, rustyrump! it's just too easy
to get you to be as predicable as you really are and make you reveal
yourself for what you truly are, which is a . . . quack, quack, quack,
quack, quack.

kate
(LOL! too funny! almost sad, but too funny.)

Numbnutz wrote:


Don't you know everyone else in these groups are sick and tired of you and
your stupidity?



What do you take for your pain?


.... Numbnutz tommy: Like a rock, only dumber.

On Sep 10, 6:13 pm, "d'huit" <threeceda...@comcast2.net> wrote: reveal
yourself for what you truly are, which is a . . . quack, quack, quack,
quack, quack. <<

Sooo .. since hyperlipidaemia .. IS .. hyperviscosity .. and YOU ..
say it .. "isn't" / "quack, quack, quack,
quack, quack" {I'll assume that is what you mean here .. since you are
soo fkdup one cannot tell] .. even with supplied study / science ..
makes YOU .. **stupid** ..

You can .. say .. "he's stupid" .. but technically you have to
prove .. it .. and WHEN you try .. ?

You prove **yourself** to be .. stupid ..

But the thing about stupidity .. is .. ?

You are too stupid to be able to understand / see .. the conclusion BY
the medical **researchers**.IE:Se-Joong Rim, MD; Howard Leong-Poi, MD;
Jonathan R. Lindner, MD; Kevin
Wei, MD; Nicholas G. Fisher, MD; Sanjiv Kaul, MD

That is **six** / 6 .. doctors ..

That whole circle of life / stupidity .. dealy ..

Sooo .. you go on thinking hyperlipidemia and hyperviscosity are
NOT .. the **same** .. or more **precisely** hyperlipidaemia does NOT
manifest / does NOT **cause** hyperviscosity ./ increased
viscosity ..

OK .. ?

That is very .. good ..

Now keep your personal remarks to yourself ..

It is .. unbecoming of a .. lady ..

Oh .. yeah .. that's right ..

Heh .. heh ..


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

"ironjustice" <teamtanner@hotmail.com> wrote in message
news:1189476208.545232.4360@r34g2000hsd.googlegrou ps.com...
On Sep 10, 6:13 pm, "d'huit" <threeceda...@comcast2.net> wrote: reveal
yourself for what you truly are, which is a . . . quack, quack, quack,
quack, quack. <<

Sooo .. since hyperlipidaemia .. IS .. hyperviscosity .. and YOU ..
say it .. "isn't" / "quack, quack, quack,
quack, quack" {I'll assume that is what you mean here .. since you are
soo fkdup one cannot tell] .. even with supplied study / science ..
makes YOU .. **stupid** ..

You can .. say .. "he's stupid" .. but technically you have to
prove .. it .. and WHEN you try .. ?

You prove **yourself** to be .. stupid ..

But the thing about stupidity .. is .. ?

You are too stupid to be able to understand / see .. the conclusion BY
the medical **researchers**.IE:Se-Joong Rim, MD; Howard Leong-Poi, MD;
Jonathan R. Lindner, MD; Kevin
Wei, MD; Nicholas G. Fisher, MD; Sanjiv Kaul, MD

That is **six** / 6 .. doctors ..

That whole circle of life / stupidity .. dealy ..

Sooo .. you go on thinking hyperlipidemia and hyperviscosity are
NOT .. the **same** .. or more **precisely** hyperlipidaemia does NOT
manifest / does NOT **cause** hyperviscosity ./ increased
viscosity ..

OK .. ?

That is very .. good ..

Now keep your personal remarks to yourself ..

It is .. unbecoming of a .. lady ..

Oh .. yeah .. that's right ..

Heh .. heh ..


Who loves ya.
Tom


sheesh! your mind really IS predictably filled with rust for brains. try
this, in a more elementary form: "if it looks like, sounds like and acts
like a duck, then it IS a duck." and "if it looks like, sounds like and acts
like a mindlessly obsessive, raving lunatic, then it IS a mindlessly
obsessive, raving lunatic." now, do you get it? however, i suspect you
will never comprehend the pun. so, i won't waste my energy trying to
explain it to you.

kate

On Sep 10, 7:43 pm, "d'huit" <threeceda...@comcast2.net> wrote:so, i
won't waste my energy trying to
explain it to you. <<

You keep .. prattling .. on .. don't ya ..

You have no idea what the article says .. yet .. you seem to be acting
like you .. do ..

Now which is it .. ?

You DO .. understand the article .. ?

Or you .. don't ..

Which is it ..

Does milkshake make milk thicker .. ?

Does it .. ?

Pretty simple .. question ..

Answer it ..

You seem to be attempting to .. belittle this .. thread ..

Now why would you try to do .. that ..

Because you don't .. understand the .. article .. ?

That is not a good reason ..

Stupidity is never a good reason to .. argue a .. point ..

It is a bad place for you to .. start ..

<<snip>>
the hyperviscosity syndrome is strongly **dependent** upon the
**lipid** .. profile.
<<snip>>

Clin Hemorheol Microcirc. 2006;35(1-2):207-12. Links
Hemorheological disturbances correlate with the lipid profile but not
with the NCEP-ATPIII score of the metabolic syndrome.
Aloulou I, Varlet-Marie E, Mercier J, Brun JF.
Université Montpellier 1, UFR de Médecine, Laboratoire de Physiologie
des Interactions, Montpellier Institut de Biologie, Boulevard Henri
IV, F-34062 France.

The metabolic syndrome, which is associated with an high risk for
diabetes and atherothrombosis, is associated with hemorheologic
abnormalities. These abnormalities seem more and more to be explained
by its various symptoms than by insulin resistance which represents
theoretically the core of the syndrome. In this study we aimed at
defining the specific hemorheologic profile of insulin resistance and
hyperinsulinemia by separating a sample of 90 subjects into 4
subgroups according to the clinical score "NCEP-ATPIII" which is the
best recognized standardized definition of the syndrome. Results show
no significant changes of blood rheology across classes of NCEP score
despite a borderline rank correlation between RBC aggregability "M1"
and the score. Whole blood viscosity was mostly correlated to HDL-
cholesterol (r = -0.353, p = 0.007) and triglycerides (r = 0.574, p =
0.0001). Plasma viscosity was correlated with total cholesterol (r =
0.3359, p = 0.02) and with LDL-cholesterol (r = 0.357, p = 0.03). Red
blood cell rigidity "Tk" was negatively correlated to HDL-cholesterol
(r = -0.430, p = 0.007). Aggregability "M" was correlated to total
cholesterol (r = 0.356, p = 0.01) and "M1" to HDL-cholesterol (r =
-0.406, p = 0.006). Thus, despite previously described correlations
with glucose disposal parameters, the hyperviscosity syndrome of the
metabolic syndrome is not proportional to its clinical scoring and is
strongly dependent upon the lipid profile.

PMID: 16899929 [PubMed - indexed for MEDLINE]


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

Take away the lipids and you have .. "significant reductions in whole
blood viscosity at all shear rates."

Am J Cardiol. 2004 Apr 15;93(8):1044-6. Links
Effect of low-density lipoprotein cholesterol apheresis on blood
viscosity.
Moriarty PM, Gibson CA, Kensey KR, Hogenauer W.
University of Kansas School of Medicine, Kansas City, Kansas, USA.
pmoriart@kumc.edu

Few studies have been designed to study the hemodynamic effects of low-
density lipoprotein apheresis, especially on whole blood viscosity.
Six patients with cardiovascular disease and hypercholesterolemia
underwent a single low-density lipoprotein apheresis, resulting in
significant reductions in whole blood viscosity at all shear rates.

PMID: 15081454 [PubMed - indexed for MEDLINE]


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

Tommy,

When are you coming to visit? I've even vacuumed out the car making
everything ready

Cheers mate!

Yes, I agree with you. Its almost like picking on a cripple.
Harv

"california_chief" <Fire_Chief@Jamacha_Junction_FD.ca.us> wrote in message
news:JfmFi.32$wZ1.29@newsfe14.lga...
Please,,, just let it go Chief.
Harv