- psoriatic arthritis & severely underactive thyroid - any advice?!
- Posted by ship
Hi
Please excuse the cross-post. But good female friend of mine has just
been diagnosed with:
a) psoriasis
b) psoriatic arthritis
c) underactive thyroid
Now I can't but help think that all these things are related!
She has been put on "Methotrexate" by her GP.
She is 42 years old, and had been healthy for years (apart from
18months off work with [proven] toxoplasmosis, btw.
Here's what she says herself about her condition:
I've been diagnosed with:
an underactive thyroid - initial blood result in May 04 was TSH of 47
(norm: 0.3-5.00)
Prescribed Thyroxin increasingly up to 175mg and 150mg alternating
days:
now TSH of 1.12, T4 of 17 (norm 11-23), T3 of 3.7 (3.5-6.5)
Key symptoms:
loss of hair
loss of energy, sluggish
putting weight back ON although only 4 months past C-section.
slow metabolism
feeling cold and low temperature on thermometer
slow pulse
Aching muscles - barely able to get out of bed, or up stairs
Taking steps one at a time with both feet.
psoriatic arthritis
I've had scalp psoriasis for about 6 years, not too severe & responded
well to treatment in between pregnancies
Suddenly developed Painful joints & muscles as above, particularly feet
esp left ankle
Key Symptoms:
a 'sausage' toe - big, swollen stiff 2nd toe on left foot - now settled
but 'clawing', won't stretch out easily - danger of calcification.
Increasingly painful feet - base joints of little toes, achilles,
outside edge of feet, in under heel, achilles heel and (mainly) joint
of left ankle. Decreasing movement in ankle joint and permanent heat &
swelling (not dramatic, just puffy & hot) in the ankle.
Right thumb is a bit stiff. Neck stiffens regularly & doesn't settle
after usual osteo treatment
Treatment:
Started end Jan 7.5 of Methotrexate (one of 5 most toxic drugs
prescribed) to stop my immune system attacking my body... Blood checked
every 2 weeks for side effects... Also taking diclofenac something, a
anti-inflamatory 2x75mg each day to make walking manageable.
But nails fine, back broadly fine
Anyone with any of these diseases - any tips??
I am trained as a scientist but I must confess that
I am biased towards holistic/alternative medicines.
I have various hormonal issues myself:
subclinical hypothyroid & reactive hypo-glycemia (moderate) and
long-standing (15+ years) CFS, and IBS (irritable bowel symdrome)
myself.
I have a sneaking suspicious that a parasite could be
involved and that our family all have the parasite.
e.g. Round worms, liver flukes etc
[If in doubt see this on round worms:
http://www.energywave.com/what-ails-...ic-Fatigue.htm
]
Any advice anyone?!
Ship
Shiperton Henethe
- Posted by Harvey R. Stone
Hi Ship,,,, For several reasons, she should see a Rheumatologist. There
are new medicines to help with PA.
Harv
"ship" <shiphen@yahoo.com> wrote in message
news:1111423651.588730.224950@f14g2000cwb.googlegr oups.com...
- Posted by Kevin G. Rhoads
OK both of the key thyroid hormones, T3 & T4, are in range -- BUT
T3 is on the LOW side and just barely in range, and TSH is higher
than would often be desireable in someone on thyroid hormone replacement.
Suggest the 175 alternating with 150 mcg of T4 be changed to straight
150mcg and 5mcg T3 twice a day be added to bring total thyroid dose
up a bit and balance T3 better against T4. If hypo-thyroid symptoms
persist, a slight increase of T3 or of T4 could be tried after that.
Discuss this with your doctor(s).
So long as the thyroid is not quite right, this can exacerbate other
symptoms of the psoriasis and arthritis &c. So don't let the doctors
back-burner this while pursuing the other things...
- Posted by ship
Harvey
Thanks. I believe it was a "rheumatologist" who gave her the
"Methotrexate".
Can you recommended any specific medicines?
Personally my hunch is that a more holistic approach is needed. Surely
her hypothyrodism *has* to be linked to her "psoriatic arthritis"!
But the trouble with western medicine is that they look at diseases one
at a time rather than the integrerated whole system!
For example if she does have some parasite, causing say poor nutrition,
and/or hormonal imbalances... and/or food sensitivities what hope would
she have of a rheumatologist spotting it.
It seems you need to go to the right specialist to get the right
medication and to knock the problem on the head with the right drug...
I'll get back to you to confirm that if she's actually seen a medic
calling himself a "rheumatologist" though!
Ship
Shiperton Henethe
- Posted by randall
Hi Ship,
You said:
Please excuse the cross-post. But good female friend of mine has just
been diagnosed with:
a) psoriasis
But below she or you say that her P onset six years ago.
And then went thru two child births etc.
So she onset at 36. What happened back then prior to that?
Strep or anything requiring antibiotics, perhaps?
Or how about lithium or other Rx drugs?
b) psoriatic arthritis
c) underactive thyroid
Now I can't but help think that all these things are related!
She has been put on "Methotrexate" by her GP.
While everything is connected, the biggest one for P is most likely due
to genes.
And MTx isn't a cure. Are you and her into alternatives?
But MTX can be a license for one to continue destructive behaviors if
some of her problems are due to her current diet.
Certainly though, the diet for P is the least desirable route for most
to contemplate. But some veggie/Pagano/high fiber/ DASH/ diets do seem
to help.
She is 42 years old, and had been healthy for years (apart from
18months off work with [proven] toxoplasmosis, btw.
Ok!
Here's what she says herself about her condition:
I've been diagnosed with:
an underactive thyroid - initial blood result in May 04 was TSH of 47
(norm: 0.3-5.00)
Prescribed Thyroxin increasingly up to 175mg and 150mg alternating
days:
now TSH of 1.12, T4 of 17 (norm 11-23), T3 of 3.7 (3.5-6.5)
Key symptoms:
loss of hair
loss of energy, sluggish
putting weight back ON although only 4 months past C-section.
slow metabolism
feeling cold and low temperature on thermometer
slow pulse
Aching muscles - barely able to get out of bed, or up stairs
Taking steps one at a time with both feet.
psoriatic arthritis
I've had scalp psoriasis for about 6 years, not too severe & responded
well to treatment in between pregnancies
Suddenly developed Painful joints & muscles as above, particularly feet
esp left ankle
Sounds like gout or PsA has set in now.
And you already have the info from other posts on correcting
the thyroid for the time being. BTW, my father has been on
thyroid and has had P for around 37 years now.
Key Symptoms:
a 'sausage' toe - big, swollen stiff 2nd toe on left foot - now settled
but 'clawing', won't stretch out easily - danger of calcification.
Increasingly painful feet - base joints of little toes, achilles,
outside edge of feet, in under heel, achilles heel and (mainly) joint
of left ankle. Decreasing movement in ankle joint and permanent heat &
swelling (not dramatic, just puffy & hot) in the ankle.
Right thumb is a bit stiff. Neck stiffens regularly & doesn't settle
after usual osteo treatment
Treatment:
Started end Jan 7.5 of Methotrexate (one of 5 most toxic drugs
prescribed) to stop my immune system attacking my body... Blood checked
every 2 weeks for side effects... Also taking diclofenac something, a
anti-inflamatory 2x75mg each day to make walking manageable.
But nails fine, back broadly fine
Anyone with any of these diseases - any tips??
Not I, but do have P. Have had PsA with the crooked digits to prove it.
And felt craPPy for years. Is that like CFS?
I am trained as a scientist but I must confess that
I am biased towards holistic/alternative medicines.
And how does your female friend feel about that?
What does her diet look like now? Is she willing to
work with it?
I have various hormonal issues myself:
subclinical hypothyroid & reactive hypo-glycemia (moderate) and
long-standing (15+ years) CFS, and IBS (irritable bowel symdrome)
myself.
Did she kiss that cat, then you?
lol
I have a sneaking suspicious that a parasite could be
involved and that our family all have the parasite.
e.g. Round worms, liver flukes etc
What? Now your sounding like Hulda Clark. Your flukes are morphing into
quacks. lol
[If in doubt see this on round worms:
http://www.energywave.com/what*-ails...s/ne*w-parasit....
]
http://groups-beta.google.com/group/...c8963b60c49b33
This goes back to 2000!
Shouldn't they have found it by now?
http://www.anapsid.org/cnd/diffdx/klapow2.html
This doesn't go anywhere. Cept round in circles.
Why couldn't her problem just be generic off the shelf
LPS (endotoxins) in a *leaky* gut ?? Due to something that
happened when she onset?
She has the genes for P, PsA in addition to her low thyroid problems
most likely.
Any advice anyone?!
If she has P and PsA and wants to change diet things, can you get her
to google this group for diet tips?
Go to www.deja.com and enter psoriasis diet (and any other keywords)
like
AA or fish, terry fenris etc
Ship
Shiperton Henethe
Good luck Ship. I hope that her derm can work with her other doctors to
set things right. And if any diet tips work for her
from this group please let us know.
randall
- Posted by drceephd2@netscape.com
ship wrote:
What you experiencing is the quackery of allopathic medicine.
The body does not attack itself, chemotherapy is not needed for
arthritis, and psoriasis is a colon disorder showing up in the skin.
All the symptoms you have described are symptoms of a degenerating
body, not some specific disease. You will have to treat the whole body
to get the symptoms and the diseases to abate.
Try to find a copy of the book "A doctor's proven home cure for
arthritis" by a DO with a last name of Renauld. His advice will be
very worthwhile.
You will also find Diamond's book "Fit for life" Vol. I to be helpful
in avoiding indigestion and helping the colon to recover.
Arthritis is caused by an overly acidic dietary which causes the body's
tissues to become acidic rather than alkaline. This causes the enzymes
in the joint tissues to malfunction and allows all the symptoms of
arthritis to manafest themselves. You must correct the acid/alkaline
imbalance and provide for correct nutrition and exercise to rebuild.
DrC PhD
- Posted by paula
comments inserted
ship wrote:
Be careful, be very careful. I was on imuran, also an immunosuppressant. never!!
again. Started to do weird ( like nut house case) things. Also, have her watch
very carefully for shingles. When not in time for treatment ( starts looking
like a pimple but you get very deep pain, but not constant) one can have very
severe pain for over a year. I got it twice in a row, normally very unusual to
get it twice in a lifetime!!
T3 is to low IMHO. All symptoms can be due to not properly treated hypo thyroid.
Either add cytomel or go over onto armour thyroid; at least that is what I would
do.
Many of the above could be allergy related as well. I would check that out just
in case.
If parasites are suspected and the Doc won't do anything, I strongly advice the
zapper and treatment from Dr. Hulda Clark. I myself have crohn's and diarrhea
was extremely severe, incl. incontinence. No Crohn's medications helped ( incl.
prednisone and imuran) but I bought the zapper and although I have to do it
daily, no more diarrhea ( although rather loose stools). It really gave me some
sort of life back. It is not expensive and very safe. In europe it is a class
IIa medical device.
Hope that helps
- Posted by randall
Hey Ship!
Where did the conversation go today?
Did I trip over someones pride? Was it you?
Do you want to get your gal pal well or not?
Or are you guys inadvertently shilling hulda? lol
Lets pretend you and HER really are into alt
nostrums. And your scientific bent is true!
Here's a gut twister!
Rebuild the good flora in the GUT with this,
www.thewholewhey.com Get the implant and do
the diet and cleanse program and then see what
happens to your alkaline conditions and *LEAKY* guts.
A few pounds (one killo) of good gut flora makes you
happy!
Where does this stuff start?
And whats the relationship of
Milk and melatonin!
Since I wasn't breast fed I can't tell you much about that.
I can tell you how I had to overcome my funky guts as
well as many years of topical psoriasis. But I have a pet
few percent of the stuff to still remind me!
But I've also had melatonin related problems most of my life that a
1mg.
tab every other night or so doesn't completely get rid of. But
certainly helps
so much that i've mentioned it a few dozen times gleefully. 
And caused me to wonder why it works up till now.
And science caught up to me. And your crossposted thread
dredged it alll up again and a fresh pubmed and bingo.
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=15775810
The other culprit found in the body of IMIDs folks is LPS,
so lets skew this milk/melatonin/ thing towards endotoxins (LPS),
This first one is for those asthma people, (LPS in Lungs)
(imid = immune mediated inflammatory disorder)
(ALL imids are ramped up by cell wall of endotoxins, aka-LPS)
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=15769302
Serial analysis of gene expression in mice with lipopoly-saccharide
(LPS) -induced acute lung injury.
OBJECTIVE: To monitor the systemic gene expression profile in a murine
model of lipopolysaccharide-induced acute lung injury. METHODS: Acute
lung injury was induced by intratracheal injection of
lipopolysaccharide in 3 mice. Another 3 normal mice receiving same
volume of normal saline were taken as the controls. The comprehensive
gene expression profile was monitored by the recently modified long
serial analysis of gene expression. RESULTS: A total of 24670 tags
representing 12168 transcripts in the control mice and 26378 tags
representing 13397 transcripts in the mice with lung injury were
identified respectively. There were 11 transcripts increasing and 7
transcripts decreasing more than 10 folds in the
lipopolysaccharide-treated mice. The most overexpressed genes in the
mice with lung injury included serum amyloid A3, metallothionein 2,
lipocalin 2, cyclin-dependent kinase inhibitor 1A, lactate
dehydrogenase 1, melatonin receptor, S100 calcium-binding protein A9,
natriuretic peptide precursor, etc. Mitogen activated protein kinase 3,
serum albumin, complement component 1 inhibitor, and ATP synthase were
underexpressed in the lung injury mice. CONCLUSIONS: Serial analysis of
gene expression provides a molecular characteristic of acute lung
injury.
PMID: 15769302
LPS turns on the genes that make your symptoms that aim to keep one
alive?
Is lps doing some thing in the brain also?
Can't sleep during the winter? How about someone who falls asleep any
old time?
Wouldn't that lend a clue or two? What does LPS do to your sleep
patterns?
Effects of inflammation produced by chronic lipopolysaccharide
administration on the survival of hypocretin neurons and sleep.
The number of hypocretin-containing neurons is markedly decreased in
most patients with the sleep disorder narcolepsy. It is presently not
known why the loss of hypocretin neurons occurs in these patients. In
the present study, we tested the role of inflammation in the
degeneration of hypocretin neurons. The proinflammagen
lipopolysaccharide (LPS) was infused chronically for 30 days (flow
rate=0.22 microg/h) into the lateral hypothalamus in rats. Compared
with chronic infusions of phosphate-buffered saline (PBS), LPS
infusions produced a decline in the number of hypocretin (29.7%
reduction), melanin concentrating hormone (MCH; 24.7% reduction), and
neuronal nuclear antigen (NeuN)-immunoreactive neurons, as well as a
dense distribution of reactive astrocytes and microglia within the
lateral hypothalamus. LPS infusions also produced a large increase in
the amounts of wakefulness 6 days after the onset of infusion
(72.5+/-8.7% of wakefulness during lights-on period compared with
45.3+/-1.8% in PBS-treated rats). Amounts of wakefulness returned to
control levels in all LPS-treated rats 30 days after the onset of
infusion. A single injection of LPS (1, 5, or 10 microg) did not
produce a significant decline in the number of hypocretin, MCH, or
NeuN-positive neurons. The loss of hypocretin neurons produced by
chronic LPS administration suggests that inflammation may play a role
in the loss of hypocretin neurons in narcolepsy.
PMID: 15306250
Does winter make you SAD? Do you want to be glad?
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=15771558
[snip] Although the mechanism(s) behind this disease is not fully
known, one treatment appears to address each of the theories. Light
therapy is a natural, non-invasive, effective, well-researched method
of treatment for SAD. Various light temperatures and times of
administration of light therapy have been studied, and a combination of
morning and evening exposure appears to offer the best efficacy. Other
natural methods of treatment have been studied, including L-tryptophan,
Hypericum perforatum (St. John's wort), and melatonin.
PMID: 15771558
Is Melatonin coming from your Brain? Maybe not,
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=15683461
Melatonin was thought to originate primarily from the pineal gland and
to be secreted during the night, but recent studies revealed that
gastrointestinal (GI) tract presents another, many times larger, source
of melatonin that contributes significantly to the circulating
concentration of this indole. Melatonin may exert a direct effect on GI
tissues but its major influence on GI organs seems to occur indirectly,
via the brain-gut axis including peripheral receptors, sensory afferent
(vagal or sympathetic) pathways and central nervous system (CNS) acting
on these organs via autonomic efferents and neuromediators. [snip]
Although exerting certain differences in the mechanism of action on
gastric and pancreatic secretory activities, melatonin derived from its
precursor L-tryptophan, exhibits similar highly protective actions
against the damage of both the stomach and the pancreas and accelerates
the healing of chronic gastric ulcerations by stimulating the
microcirculation and cooperating with arachidonate metabolites such as
prostaglandins, with nitric oxide released from vascular endothelium,
and/or sensory nerves and with their neuropeptides such as calcitonin
gene related peptide. The beneficial effects of melatonin results in
gastro- and pancreato-protection, prevents various forms of gastritis
and pancreatitis through the activation of specific MT2-receptors and
scavenges reactive oxygen species (ROS). Melatonin counteracts the
increase in the ROS-induced lipid peroxidation and preserves, at least
in part, the activity of key anti-oxidizing enzymes such as superoxide
dismutase. It is proposed that melatonin should be considered as the
agent exerting an important role in prevention of gastric and
pancreatic damage and in accelerating healing of gastric ulcers.
PMID: 15683461
You gotta fix those guts. Hulda's zapper doesn't fix those does it?
Paula said she uses it regularly. Is she prolonging an alkaline
condition?
Yes!
How much is to much of a good thing? When it comes to melatonin you may
only
need to take the 1 mg size and cut it into thirds!
http://www.sciencedaily.com/releases...0308134331.htm
Some nights I take 3 mg.s and other nights none. And I know folks who
have a problem with 1 mg. anytime. Bad dreams and feeling woozy etc.
But see below for how much you may need.
For all of us in the psoriasis newsgroup there are also P/ melatonin /
serotonin links coming from science recently,
Serotonin and melatonin links to skin biology,
http://groups-beta.google.com/group/...54ff51af3e17d6
Just so you don't have to check these links,
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=15677341
The cutaneous serotoninergic/melatoninergic system: securing a place
under the sun.
It was recently discovered that mammalian skin can produce serotonin
and transform it into melatonin. Pathways for the biosynthesis and
biodegradation of serotonin and melatonin have been characterized in
human and rodent skin and in their major cellular populations.
Moreover, receptors for serotonin and melatonin receptors are expressed
in keratinocytes, melanocytes, and fibroblasts and these mediate
phenotypic actions on cellular proliferation and differentiation.
Melatonin exerts receptor-independent effects, including activation of
pathways protective of oxidative stress and the modification of
cellular metabolism. While serotonin is known to have several roles in
skin-e.g., pro-edema, vasodilatory, proinflammatory, and
pruritogenic-melatonin has been experimentally implicated in hair
growth cycling, pigmentation physiology, and melanoma control. Thus,
the widespread expression of a cutaneous seorotoninergic/melatoninergic
syste,m(s) indicates considerable selectivity of action to facilitate
intra-, auto-, or paracrine mechanisms that define and influence skin
function in a highly compartmentalized manner. Notably, the cutaneous
melatoninergic system is organized to respond to continuous stimulation
in contrast to the pineal gland, which (being insulated from the
external environment) responds to discontinuous activation by the
circadian clock. Overall, the cutaneous serotoninergic/melatoninergic
system could counteract or buffer external (environmental) or internal
stresses to preserve the biological integrity of the organ and to
maintain its homeostasis.-Slominski, A. J., Wortsman, J., Tobin, D. J.
The cutaneous serotoninergic/melatoninergic system: securing a place
under the sun.
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=15679607
[snip] In mammals, two types of high-affinity membrane melatonin
receptors, MT1 and MT2 have been identified, which inhibit adenylate
cyclase activity to decrease the intracellular level of cAMP.
Low-affinity membrane receptor MT3/QR2 have also been identified,
though the mechanism has not been cleared yet. Melatonin is also a
natural ligand of nuclear transcription factor ROR(alpha and beta),
which is suggested to regulate cell cycle negatively via target gene
such as p21(WAF/CIP1). Due to its lipophilic structure, melatonin also
enters through both the plasma and nuclear membrane, and acts as a
potent free radical scavenger to protect macromolecules, in particular
DNA [snip]
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=15676032
(Topical melatonin may protect against X-rays/ Sun rays???)
Do you have a hard time sleePing some time?
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=11955797
3-5 mg's of Melatonin may fix that problem.
[snip] Melatonin profiles are a diagnostic tool to distinguish between
several forms of depression, like major depression, winter depression
(SAD), unipolar depression, delayed sleep phase syndrome (DSPS). In
patients with a major depression success with antidepressants
correlated with an increase in their melatonin profiles but only
patients suffering from DSPS can be successfully treated with
melatonin. [snip]
Melatonin to correct skin pigment problems,
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=14592800
Melatonin,
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=15357831
Melatonin (5-methoxy N-acetyltryptamine) is a hormone synthesized and
released from the pineal gland at night, which acts on specific high
affinity G-protein coupled receptors to regulate various aspects of
physiology and behaviour, including circadian and seasonal responses,
and some retinal, cardiovascular and immunological functions.[snip]
^^^^^^^^^^^^^^
And now those scientists and you know that the big melatonin
also comes from the gut. All the connections just aren't clear yet!
But if yours is broke, your probably up late wondering why your
such a NIGHT OWL.
Fix and heal the gut and sweet dreams via your
own alternative well functioning mind and body! Why
get hooked on things that don't really cure you?
randall.... that was fun! I hope ship and friends come back again!
- Posted by Harvey R. Stone
"ship" <shiphen@yahoo.com> wrote in message
news:1111428483.940807.218450@o13g2000cwo.googlegr oups.com...
going to pay for them counts a lot too. When you get above Methx and
Arava,,, the price jumps up a great deal.
Hhhm, holistic ???? You would know more about that than I and it may not be
linked at all.
Those things you might do something about yourself.
There are a couple of things you need to accept,,,,, One- there is no cure
for inflam.arth. Two- there are plenty of people that will take your
money and time with very poor results.
Harv
- Posted by Harvey R. Stone
Harv
- Posted by George Lagergren
ship wrote:
Personally my hunch is that a more holistic approach is needed.
Surely her hypothyrodism *has* to be linked to her "psoriatic arthritis"!
But the trouble with western medicine is that they look at diseases
one at a time rather than the integrerated whole system!
<drceephd2@netscape.com> replied:
What you experiencing is the quackery of allopathic medicine.
The body does not attack itself, chemotherapy is not needed for
arthritis, and psoriasis is a colon disorder showing up in the skin.
So the lady with arthritis might benefit by taking
probiotics?
All the symptoms you have described are symptoms of a degenerating
body, not some specific disease. You will have to treat the whole body
to get the symptoms and the diseases to abate.
It would be helpful to know the diet lifestyle for this
lady.
But does one get a person to cut back on their sugar
intake?
Arthritis is caused by an overly acidic dietary which causes the body's
tissues to become acidic rather than alkaline. This causes the enzymes
in the joint tissues to malfunction and allows all the symptoms of
arthritis to manafest themselves. You must correct the acid/alkaline
imbalance and provide for correct nutrition and exercise to rebuild.
Also taking supplemental digestive enzymes may help with
arthritis.
But how many lay persons or even "smart" M.D.s
understand how and why an acid/alkaline Ph level imbalance
affects the health of one's body in a NEGATIVE way?
- Posted by nambucca
"ship" <shiphen@yahoo.com> wrote in message
news:1111423651.588730.224950@f14g2000cwb.googlegr oups.com...
Number 1 recomendation ........get off all those toxic drugs including
Thyroxine/synthyroid ..........switch to Armour natural Thyroid and hey
presto all the 3 diseases will probably disapear under 1 banner
The Psoriasis etc is simply an extreme manifestation of the underactive
thyroid
Synthyroid/thyroxine is a synthetic drug as are the other 2 i will bet my
sweet life you are chemically allergic
Clean up your entire diet to eating only natural fresh foods add Armour and
give it a chance to work
- Posted by randall
Hi nambucca,
You said:
[snip]
&
So, your saying P is hyPo T !!?? T being thyroid, NoPe!
It is more like hyPer TH1 (T helper 1) cells with P genes!!!
Could you be relying on the Dr.Ray Peat page (found at the end of this
post) (***)?
If you had checked this group first you would know that Leptin controls
thyroid.
http://groups-beta.google.com/group/...thyroid&qt_g=1
(Read the entire second post to this thread--- *Psoriasis and
Thyroid*--)
In this group, high and low thyroid problems fall about half and half
with folks WITH the same good old psoriasis. HyPo or HyPer makes
no big difference with P. Certainly the rest of the hyPo or hyPer
Thyroid
folks don't get psoriasis. Now do they?
Personally, I did the diet from the book (Mastering Leptin) to have the
homeostatic exact leptin levels. No help!
With good levels of leptin I did feel great!
But,
Does that mean YOU made the wrong call,
http://www.wrongdiagnosis.com/p/psoriasis/causes.htm
Cause of Psoriasis: Recent research indicates that psoriasis is likely
a disorder of the immune system. This system includes a type of white
blood cell, called a T cell, that normally helps protect the body
against infection and disease. Scientists now think that, in psoriasis,
an abnormal immune system causes activity by T cells in the skin. These
T cells trigger the inflammation and excessive skin cell reproduction
seen in people with psoriasis. 1
Triggers list for Psoriasis: The list of triggers mentioned in source
as possible causal factors for Psoriasis includes:
Streptococcus infection - may trigger Guttate psoriasis.
Skin injury
(But no thyroid in this list!)
[snip]
Did you mean ANTi-Thyroid??
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=14975517
Anti-thyroid thioureylenes in the treatment of psoriasis.
Psoriasis is a common skin disorder associated with significant
morbidity. Many agents are used in the medical management of this
debilitating condition with the newer anti-cytokine agents being the
most recent addition to the pharmacological armamentarium to battle the
disorder. Cost concerns are very important with the newer "biologic"
treatments costing in excess of 10,000 US dollars annually. The need
for cheaper, orally administered agents is therefore imperative. This
paper addresses the potential role of anti-thyroid thioureylenes,
propylthiouracil and methimazole, in the treatment of psoriasis and
reviews the possible mechanism of action of these drugs in this
disorder. It is hypothesized that the beneficial effect of anti-thyroid
thioureylenes in psoriasis is linked to their effect as
anti-proliferative agents as reflected by significant decrease in
markers of cellular proliferation such as proliferative cell nuclear
antigen in biopsy specimens after treatment with these drugs.
Propylthiouracil has been shown to bind to the hepatic T 3 receptor and
it is possible that propylthiouracil (6-n-propyl-2-thiouracil) binding
to the ligand-binding site normally occupied by T 3 impairs
transcription by inactivating the effect of T 3 as well as by
squelching retinoic X receptor heterodimer formation with other
receptors of the steroid receptor superfamily such as the peroxisome
proliferator-activated receptor, retinoic acid receptor and vitamin D
receptors.
PMID: 14975517
Maybe you mean using thyroid toPically?
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=15327560
Inefficacy of topical thyroid hormone analogue TriAc in plaque
psoriasis: results of a double-blind placebo-controlled trial.
BACKGROUND: Thyroid hormone receptors are expressed in human skin and
are believed to be involved in the regulation of epidermal
proliferation and differentiation, i.e. processes which are disturbed
in psoriatic skin lesions. Ligands of the thyroid hormone receptors
have so far not been tested as antipsoriatic agents. TriAc
(3,3',5-triiodo-thyroacetic acid) is a well-known thyroid hormone
analogue with much reduced cardiac thyrotoxic activity compared with
the classical thyroid hormones. OBJECTIVES: To determine the
effectiveness and side-effects of topical TriAc in patients with
chronic plaque psoriasis. METHODS: Twelve patients with mild to
moderate psoriasis were treated with TriAc (0.1% in hydrophilic
ointment) and placebo applied twice daily to either of two (or several)
bilaterally symmetrical plaques for 8 weeks. The patients and
investigator were blinded as to the content of the tubes. Every 2 weeks
the treated plaques were evaluated by the patient (using a balanced
visual analogue scale for a right-left comparison) and by the
investigator (using a psoriasis severity index and a global assessment
of each plaque). RESULTS: After 8 weeks of treatment, more than 33%
improvement of the psoriasis index occurred in 10 of 12 TriAc-treated
and nine of 12 placebo-treated plaques. There were no statistically
significant differences between the treatments in terms of reduction of
the scores for erythema, scaling, induration or pruritus during the
study. Half of the patients considered TriAc superior to placebo,
whereas three of 12 were of the opposite opinion (P > 0.05). The global
assessment showed marked improvement or remission in six TriAc-treated
and five placebo-treated cases (P > 0.05 for difference). No adverse
effects were noted. CONCLUSIONS: TriAc in the dosage and formulation
studied was safe but no more effective than placebo in treating plaque
psoriasis. However, newer thyroid hormone analogues (agonists or
antagonists) might be more active and should be further explored in
this context.
PMID: 15327560
Or you could mean Tobacco use and PPP/Thyroid problems?
http://www.ncbi.nlm.nih.gov/entrez/q..._uids=12702064
^^^^^^^^^^^^^########****************############^ ^^^^^^^^^^^^^^^^^^**********************
(***) Is this what caused you to make the thyroid/P connects?
http://www.healthynewage.com/what-is-psoriasis.htm
What Causes Psoriasis?
The Cause of Psoriasis has not been determined but there are many
factors associated with it such as food allergies, metabolic problems,
hypothyroidism, stress, faulty utilization of fat by the liver, and
colon problems such as buildup of toxins in an unhealthy colon.
According to Dr. Ray Peat and others, low thyroid function is
associated with may skin problems, including psoriasis. When thyroid
function is low, prolactin (protein hormone of the anterior lobe of the
pituitary) increases. Excess prolactin increases cell division.
Sunlight is known to decrease prolactin formation, whereas darkness and
stress can increase prolactin levels and this is why people who suffer
from psoriasis frequently notice an improvement in their skin during
the summer months.
Helpful Tips For Combating Psoriasis.
A diet low in fried foods, processed foods, saturated fats (found in
meat and dairy products), sugar, or white flour is important. Dr John
Pagano, author of Healing Psoriasis, found that in Germany there was a
high incidence of psoriasis prior to World War II. During the war, the
disease nearly disappeared when certain foods, especially red meats,
were in short supply. After the war, as the economy recovered and the
food supply returned to pre-war standards psoriasis came back.
Supply the body with essential fatty acids that are important for all
skin disorders. Essential fatty acids aid in preventing dry skin, which
is a possible link to the faulty utilization of fat. Växa's Omegacin+
is a complete blend of essential fatty acids, which can help fight
psoriasis.
Additional digestive enzymes are needed for protein synthesis and to
aid with proper digestion. Digestin is an advanced blend of digestive
enzymes and homeopathic medicinals which aid in digestion.
A good Multi-Mineral / Vitamin such as Daily Essentials with vitamins
B, A, E, C, and D for cellular functions, is also needed for healing of
skin tissue.
A good clean colon is very important to promote the excretion of toxins
with ingredients such as apple pectin and psyllium husks which can be
found in Växa's Colon-Aid+
Topically- cold pressed flaxseed, sesame, or soybean oils can be
helpful along with applying seawater to the affected area with cotton
several times a day.
Then It goes into a sales presentation of Vaxa's Omegacin+
How about anti-Prolactin then???
BIG [SNIP]
Thanks for the opportunity to check this angle one more time.
randall.... but give me the anti-prolactin pill and let me try it
first!
- Posted by ship
Hmm... Interesting!
So it seems that Psorias, athritis and hypothyroid are all some kind of
weird immune system problem that attack the thyroid and also the
skin...
The question remains what actually causes the immune mal-functioning in
the first place. Could it still be a parasite? And/or nutritional
deficiencies?
(The patient doesnt smoke and eats fairly healthily...)
If it could be caused by colon problems, then has colonic irigation
helped anyone?
Ship
- Posted by drceephd2@netscape.com
George Lagergren wrote:
slightly acidic. To convert an unhealthy colon to a healthy one
requires poviding the colon bacteria the correct type of food to eat.
Carbohydrates do this. When the bacteria ferment the carbs short chain
fatty acids are produced which are beneficial for the colon. Adding
some corn starch to the diet further promotes the colon bacteria since
we cannot digest the starch and it readily passes on the colon. Meat
and purine producers must be avoided for a time since they procduce an
alkaline residue and ammoniated compounds in the colon making the colon
alkaline.
The diet and lifestyle will be found in the two books that I
recommended. Dr. Renauld has some very facinating X-rays of diseased
joints and what those same diseased joints looked like a few months
later when returned to health.
and not from the pig. These may aid the stomach in digesting cooked
food. Fresh fruits, melons, veggies, are loaded with enzymes and do
not require added enzymes.
None that I know of. They are not taught these simple truths because
there is no profit in it for the medical monopoly.
DrC PhD
- Posted by drceephd2@netscape.com
drceep...@netscape.com wrote:
proven new home cure for arthritis" avialble at Amazon.com
Sorry for the mistake.
DrC PhD
- Posted by randall
Hi ShiP,
You said:
Don't know exactly about the thyroid involvement. But IMIDs
are the new term for autoimmune conditions.
Immune Mediated Inflammatory Disorder s
Want to read the grail page posted by JXStern in this grouP?
Its called the Good Article thread.
Try LPS (Cell wall of endotoxin)
Yeah sure! Thats what they all say! But what was the trigger and
how severe how fast.
Sure if they want to do them the rest of their lives.
But the goal is to replace the flora (one time implant) re-grow
the good stuff and not have to ever do another colonic dealy.
And the tnf and lps gets into the small intestines not the large.
But fixing the large helps the small! Got it yet?
randall
- Posted by Paul T. Holland
other groups snipped so as to avoid the extremists:
actually, it's 'really' , Giraud W. Campbell D.O. and it's a 1972 book
[though similar tomes were issued in the late '60's] published by Parker
Publishing Company...hardly anything new, yet still not part of the
accepted theories...
and just so everyone understands, this is the publishing company that was
been sued for:
"Respondent is obtaining remittances of money through the mail by means of
the foregoing false representations"
those representations being the 'health' claims contained in health diet
books...
"CONCLUSIONS OF LAW
1. Respondent is engaged in a scheme or device for obtaining money or
property through the mails by means of false representations within the
meaning of 39 U.S.C. 3005. "
peddled at the same time they published this one by campbell - a company to
be trusted for suuuuuure...in fairness it has been put out at a later time
by other publishers.
and for the newbies - drcphd [ our old buddy who used to be honest and use
his aol addy] is one who has touted that germs don't cause disease...
"The idea of a bacterial cause of disease began in 1760. Bechamp,
1816-1895, proved that bacteria do not enter the body to cause disease
circa 1870. The Dodd sisters opened the St. Louis school for physicians and
surgeons in 1904."
"The doctor of the future will interest the patient in the care of the
human
frame, in diet, and in the cause and prevention of disease, and a medical
theory which will not include bacteria, viruses, retro-viruses, prions. or
auto-immunine excuses as the cause of any disease. "
"The practice of medicine is not scientific. The practice of medicine
fails
every test of scientific credibitlity.
If medicine were scientific, we would not belive in germs and viruses as
causes
of disease any more than a child might believe in Santa Claus."
'course now, just one example, this ignores the proven fact that certain
bacteria are the cause of most ulcers...and did you know he's
anti-vaccination?
personally, i love this one:
"Rabies is no more a threat to your life than a bite from a flea."
and:
"A correct protocol will allow the body to heal itself from every, yes
every disease.
Ergo, no "disease specific" protocol is needed."
but as to his diet theory? care to explain just 'how' it is that after more
than 30 years this 'expert' is unable to provide actual studies proving the
theory?
and just how is it that, after 3 decades, his 'diet' has not been shown by
clinical trial to actually work?
oh - that's right - you believe in the grand conspiracy...
Subject: Re: AMA's Number One Priority???
"Again, it is a disease industry. Health is just the opposite of what they
want
and need in order to make the profits they want and garner the power they
desire."
for those unfamiliar - the gist is that a dirty colon is the cause - and
while it is undisputable that some folks have an immune reaction to what is
transferred from the colon into the blood system -
that is a far cry from explaining all the myriad and diverse 'auto' immune
conditions - not to mention the traumatic injury forms, that make up the
arthritis family - but hey, what are a few facts when dealing with these
folks?????
if you want to experiance a series of coffee enemas a dictated by these
folk - feel free! not to mention the contradiction embodied in the claim
that this diet has been responsible for regrowth of hip and spine
bone...without having to actually prove it though...
for those with a long memory, this dufus is a traveling companion of the
falconblanco bunch
after removing the self-aggrandizing claims contained in the book, it boils
down to:
one more fairly reasonable thesis for improving one's diet - carried to an
extreme.
ah well... i do find it droll, and sad
paul
drceephd2@netscape.com wrote:
- Posted by George Lagergren
<drceephd2@netscape.com> wrote:
Thanks for the correction.
I have several older friends who use tons of sugar and then
wonder why they have arthritis.
I believe sugar is an acid producing food item.
- Posted by Harvey R. Stone
Hi Paul,,, I want to thank you for your on going work and I use the word
work because you do so much for this newsgroup. Please let me apologize
ahead of time to you because I am going to repeat your post to all the
groups. People need to see what this guy really is.
Sorry
Harv
"Paul T. Holland" <pholland@bellatlantic.net> wrote in message
news:424348C4.DA395F9A@bellatlantic.net...