<<snip>>
three factors--ascorbic acid deficiency, iron overload, and alcohol
abuse--contributed to the osteoporosis
<<snip>>

Ascorbic acid deficiency, iron overload and alcohol abuse underlie the
severe osteoporosis in black African patients with hip fractures--a
bone histomorphometric study.
Schnitzler CM, Schnaid E, MacPhail AP, Mesquita JM, Robson HJ
Calcif Tissue Int. 2005 Feb ; 76(2): 79-89

Osteoporosis and femoral neck fractures (FNF) are uncommon in black
Africans although osteoporosis accompanying iron overload (from
traditional beer brewed in iron containers) associated with ascorbic
acid deficiency (oxidative catabolism by iron) has been described from
sub-Saharan Africa. This study describes histomorphometric findings of
iliac crest bone biopsies and serum biochemical markers of iron
overload and of alcohol abuse and ascorbic acid levels in 50 black
patients with FNFs (29 M, 21 F), age 62 years (40-95) years (median
[min-max]), and in age- and gender-matched black controls. We found
evidence of iron overload in 88% of patients and elevated markers of
alcohol abuse in 72%. Significant correlations between markers of iron
overload and of alcohol abuse reflect a close association between the
two toxins. Patients had higher levels of iron markers, i.e., siderin
deposits in bone marrow (P < 0.0001), chemical non-heme bone iron (P =
0.012), and serum ferritin (P = 0.017) than controls did. Leukocyte
ascorbic acid levels were lower (P = 0.0008) than in controls. The
alcohol marker mean red blood cell volume was elevated (P = 0.002) but
not liver enzymes or uric acid. Bone volume, trabecular thickness, and
trabecular number were lower, and trabecular separation was greater in
patients than in controls, all at P < 0.0005; volume, surface, and
thickness of osteoid were lower and eroded surface was greater, all at
P < 0.0001. There was no osteomalacia. Ascorbic acid deficiency
accounted significantly for decrease in bone volume and trabecular
number, and increase in trabecular separation, osteoid surface, and
eroded surface; iron overload accounted for a reduction in mineral
apposition rate. Alcohol markers correlated negatively with osteoblast
surface and positively with eroded surface. Relative to reported data
in white FNF patients, the osteoporosis was more severe, showed lower
osteoid variables and greater eroded surface; FNFs occurred 12 years
earlier and were more common among men. We conclude that the
osteoporosis underlying FNFs in black Africans is severe, with marked
uncoupling of resorption and formation in favor of resorption. All
three factors--ascorbic acid deficiency, iron overload, and alcohol
abuse--contributed to the osteoporosis, in that order.


Who loves ya.
Tom


Jesus Was A Vegetarian!
http://jesuswasavegetarian.7h.com


Man Is A Herbivore!
http://tinyurl.com/a3cc3


DEAD PEOPLE WALKING
http://tinyurl.com/zk9fk

<ironjustice@aol.com> wrote in message
news:1161261635.804934.177060@m7g2000cwm.googlegro ups.com...
To all new people and older people on the return,,,,, when this post is not
answered it is because this person gets nasty when you talk good sense in
reply to iron being the cause of all mankind's problems... You can not
change a troll with honest good sense.
Please just ignore any post by ironjustice......

Harv

Now Harv, why are you picking on poor old Tommy Rust-bucket?

He's not really an anti-social moron who hates people of differing religious
beliefs, he just plays one on newsgroups.


PS- you didn't <snip> enough of his original post.

"Norman" <mr.bones@att.net> wrote in message
news:MPG.1fa1fc041382f4ec989702@127.0.0.1...
LOLOL,,,,but it needed doing and I am sure you could of done it better and
will next time. I hope you are doing well Bones.

Harv

Norman wrote:

But what is lower than moron?


He should learn to play with himself.


.... Do you know me? *I* don't.

Fire Chief wrote:
Idiot?


He did.. too much. Tha's how he got that way. ;-)

Norman wrote:

To which Joe replied:

And Bud added:

Hmmmmmm, maybe there is some truth to what fathers
tell/warn their sons about. <g>

Do you think he has hair in the palm of his hands too?


..... Do misbehaving witches get sent to the broom closet?

"Fire Chief" <CALIFORNIA_CHIEF@PEOPLEPC.COM> wrote in message
news:1161724442.464528.319280@h48g2000cwc.googlegr oups.com...
Norman wrote:

But what is lower than moron?


a petrified brain? a slug? a nematode?--nah, they're kinda cute when you
look at them through a microscope. a dirt clod? a vacuous craninum? a
rusty rump? i can go on, if you want me to.

kate


He should learn to play with himself.


.... Do you know me? *I* don't.