I guess the spin on this would be .. "poor prognosis" .. or ..
"running ability decreased" .. or .. "walking distance shortened" ..
"developed breath holding" .. ?
I wonder how long she would have survived if they would have gone
after the iron .. ?
http://hightc.cwru.edu/htc-susceptom...er-project.htm
<<snip>>
Iron overload is caused by refractory anemia .
<<snip>>
Ryumachi. 1997 Feb;37(1):30-5. Links
[A case of malignant rheumatoid arthritis associated with
myelodysplastic syndrome][Article in Japanese]
Hisakawa N, Nishiya K, Hashimoto K, Tanaka Y.
Second Department of Internal Medicine, Kochi Medical School.
The patient (57 year-old female) complained of high fever and
polyarthralgia in autumn of 1994, when a diagnosis of refractory
anemia, a type of myelodysplastic syndrome (MDS) was made by severe
anemia (RBC: 154 x 10(4)/microliters), leucopenia (2,200/microliters)
and erythroid hyperplasia, ring-nucleated myelocyte,
micromegakaryocyte and less than 5% of blasts in bone marrow smear. In
her further clinical course, symptoms such as episcleritis,
mononeuritis multiplex, skin ulcers on bilateral lower legs and
circulating disturbance on left lower leg with high titer of
rheumatoid factor were appeared in six months, suggesting malignant
rheumatoid arthritis (MRA). She also had rectal cancer notified by
anal bleeding. In spite of the administration of large doses of
glucocorticoid and disease modifying anti-rheumatic drugs, circulating
disturbance on left lower leg which might be caused by vasculitis was
worsened to show tissue necrosis. Finally, she died of disseminated
intravascular coagulation. The association of MDS with rheumatic
disorders such as rheumatoid arthritis, Behcet disease and Sjogren's
syndrome is not rarely reported. However, this is the first case of
MDS associated with MRA.
PMID: 9128421 [PubMed - indexed for MEDLINE]
Who loves ya.
Tom
Jesus Was A Vegetarian!
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DEAD PEOPLE WALKING
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